When a DPP4i is needed
Sustained efficacy up to 104 weeks*1.
Adjusted mean HbA1c values over 104 weeks†
*Study performed using a free combination of linagliptin and metformin.
†Adjusted mean change in glycated haemoglobin (HbA1c) at week 104 in the completers’ cohort. 2 year parallel-group, non-inferiority double-blind trial. Patients receiving stable metformin alone or with one additional oral antidiabetic drug (washed out during screening) were randomly assigned to linagliptin (5 mg) or glimepiride (1–4 mg) orally once daily.